Achtung:

Sie haben Javascript deaktiviert!
Sie haben versucht eine Funktion zu nutzen, die nur mit Javascript möglich ist. Um sämtliche Funktionalitäten unserer Internetseite zu nutzen, aktivieren Sie bitte Javascript in Ihrem Browser.

Data Center Building O Show image information

Data Center Building O

The HMC Suffix-Array Walker

A suffix array is a data structure that sorts all suffixes of a text string in order to allow efficient search for substrings. There are several data structures to represent suffix arrays, as well as derived structures like the Burrows-Wheeler transformation. Suffix arrays and derived data structures are often used in compression algorithms and in bioinformatics applications, where they represent DNA sequences. In the bioinformatics scenario of short read mapping, the latency of memory operations in a data- dependent random access pattern is the restricting performance factor. A recent research paper proposed a method to trade-off required memory size for number of memory access operations. However, the current work only presents one particular design point on a single hardware platform.

We have a wide range of CPU and FPGA systems, where this trade- off can be explored further. A particularly interesting platform is the recently released hybrid memory cube (HMC) manufactured by world leading memory manufacturer Micron. In this thesis, you will design a scalable short read mapping implementation with suffix-arrays and integrate it into a state-of-the-art bioinformatics application and explore it on the HMC and other hardware platforms. You can contribute to leading-edge research on the algorithmic side and work with brand new hardware systems.

Tasks

  • Memory-scalable C/C++ implementation of short read matching
  • Port to hardware with OpenCL or high-level synthesis
  • Explore memory trade-offs

Recommended Skills

  • Solid programming background (C/C++)
  • Experienced Linux user
  • Interest in new hardware

Suffix-Array Example

i1234567
A[i]7642153
1$aaabnn
2$nnaaa
3aan$n
4$naa
5an$
6$a
7$
Contact

Dr. Tobias Kenter

Paderborn Center for Parallel Computing (PC2)

Research Associate

Phone:
+49 5251 60-4340
Fax:
+49 5251 60-1714
Office:
O2.161

The University for the Information Society